Scott Minnich

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Scott A. Minnich é professor associado de microbiologia na University of Idaho[1], e pesquisador do Discovery Institute's Center for Science and Culture[2]. Minnich tem um título de bacharel em Bacteriologia e Saúde Pública da Washington State University (1975), um mestrado em Microbiologia pela University of Idaho, e um Ph.D. em Microbiologia pela Iowa State University em 1981.

Trabalho

Minnich é um proponente do design inteligente. Minnich apóia a tese de Michael Behe da "complexidade irredutível" em flagelos bacterianos como prova do design inteligente. Entre os interesses de pesquisa do Minnich estão a regulação da temperatura da expressão gênica da Yersinia enterocolitica e coordenar a expressão recíproca de genes de flagelos e virulência. Ele também foca na patogênese bacteriana da Yersinia pestis, agentes etiológicos da peste bubônica[1].

Informações de contato

Scott A. Minnich
Associate Professor
University of Idaho
Ag Biotech, Room 209
Fone: (208) 310-2477
Email: sminnich@uidaho.edu

Publicações

Livros

  • Meyer, Stephen C.; Nelson, Paul A.; Moneymaker, Jonathan; Minnich, Scott; Seelke, Ralph. Explore Evolution: The Arguments For and Against Neo-Darwinism. Malvern, Victoria: Hill House Publishers, 2009. p. 128-139. ISBN 978-0-947352-41-6

Artigos

  • Dustin J. Van Hofwegen, Carolyn J. Hovde, and Scott A. Minnich. 2015. Rapid evolution of citrate utilization by Escherichia coli K12 by direct selection requires citT and dctA. J. of Bacteriol. (provisionally accepted pending additional experiment)
  • Haiqing Sheng, Smriti Shringi, Katherine N. K. Baker, Scott A. Minnich, Carolyn J. Hovde, Thomas E. Besser. 2015. Standardized Escherichia coli O157:H7 Exposure studies in cattle provide evidence that bovine factors do not drive increased summertime colonization. Appl. Environ. Micobiol. (in press).
  • Kolodziejek AM, Caplan AB, Bohach GA, Paszczynski AJ, Minnich SA, Hovde CJ. 2013. Physiological levels of glucose induce membrane vesicle secretion and affect the lipid and protein composition of Yersinia pestis cell surfaces. Appl Environ Microbiol. 79(14):4509-14.
  • Seo K. S., J. W. Kim, J. Y. Park, A. K. Viall, S.S. Minnich, H. N. Rohde, D. R. Schnider, S. Y. Lim, J. B. Hong, B. J. Hinnebusch, J. L. O’Loughlin, G. A. Bohach, C. J. Hovde, S. A. Minnich. 2012. The role of intimin/invasin-like protein (Ilp) in Yersinia pestis virulence. Infect. Immun. 80(10):3559-69.
  • Kolodziejek A. M., C.J. Hovde, S.A. Minnich. 2012. Yersinia pestis Ail: multiple roles of a single protein. Frontiers Cell Infect. Microbiol. 2:1-10.
  • Sheng, H H, J Wang, JY Lim, C Davitt, and SA Minnich, CJ Hovde. 2011. Internalization of Escherichia coli O157:H7 by bovine rectal epithelial cells. Frontiers Microbiol. 2:32.doi:10.3389/fmicb.2011.00032. PMCID 3109292
  • Kolodziejek, A. M., Schnider, D. R., Rohde, N.H., Wojtowicz, A. J., Bohach, G. A., Minnich, S.A., and Hovde, C. J. (2010). Outer membrane protein X (Ail) contributes to Yersinia pestis virulence in pneumonic plague and its activity is dependent on the lipopolysaccharide core length. Infect Immun. 78:5233-5243.
  • Spinner, J.L., Seo, K.S., O’Loughlin, J.L., Cundiff, J.A., Minnich, S. A., Bohach, G.A., and Kobayashi, S. D. (2010). Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system. PLoS One. 5:e9279.
  • O’Loughlin, J.L., Spinner, J.L, Minnich, S. A., and Kobayashi, S. D. (2010). Yersinia pestis two-component systems protmote survival in human neutrophils. Infect Immun. 78:773-782.
  • Larson, C.L. Christensen, J.E., Pacheco, S.A., Minnich, S.A., and M.E. Konkel (2008) Campylobacter jejuni secretes proteins via the flagellar type III secretion system that contribute to host cell invasion and gastroenteritis. In: Campylobacter 3rd Ed. Eds. Nachamkin et al., ASM Press, Washington, DC
  • Airhart, C. L., H. N. Rohde, G. A. Bohach, C. J. Hovde, C. F. Deobald, S. S. Lee & S. A. Minnich, (2008a) Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague. Microbiology 154: 2131-2138.
  • Airhart, C. L., H. N. Rohde, C. J. Hovde, G. A. Bohach, C. F. Deobald, S. S. Lee & S. A. Minnich, (2008b) Lipid A mimetics are potent adjuvants for an intranasal pneumonic plague vaccine. Vaccine 26: 5554-5561.
  • Sheng, H., J. Y. Lim, M. K. Watkins, S. A. Minnich & C. J. Hovde, (2008) Characterization of an Escherichia coli O157:H7 O-antigen deletion mutant and effect of the deletion on bacterial persistence in the mouse intestine and colonization at the bovine terminal rectal mucosa. Appl Environ Microbiol 74: 5015-5022.
  • Kolodziejek, A. M., D. J. Sinclair, K. S. Seo, D. R. Schnider, C. F. Deobald, H. N. Rohde, A. K. Viall, S. S. Minnich, C. J. Hovde, S. A. Minnich & G. A. Bohach, (2007) Phenotypic characterization of OmpX, an Ail homologue of Yersinia pestis KIM. Microbiology 153: 2941-2951.
  • Minnich, S. A. & H. N. Rohde, (2007) A rationale for repression and/or loss of motility by pathogenic Yersinia in the mammalian host. Adv Exp Med Biol 603: 298-310.
  • Dobbin, H. S., C. J. Hovde, C. J. Williams & S. A. Minnich, (2006) The Escherichia coli O157 flagellar regulatory gene flhC and not the flagellin gene fliC impacts colonization of cattle. Infect Immun 74: 2894-2905.
  • V. Kapatral , J. W. Campbell, S. A. Minnich, N. R. Thomson, P. Matsumura and B. M. Pruess. 2004. Gene array analysis of Yersinia enterocolitica FlhD and FlhC: regulation of enzymes affecting synthesis and degradation of carbamoylphosphate. Microbiology 150: p. 2289-2300.
  • Monday S.R., Minnich S.A., Feng PC. 2004. A 12-base-pair deletion in the flagellar master control gene flhC causes nonmotility of the pathogenic German sorbitol-fermenting Escherichia coli O157:H-strains. J Bacteriol. 186:2319-2327.
  • Yoon J.W., Minnich S.A., Ahn J.S., Park Y.H., Paszczynski A., Hovde C.J. 2004. Thermoregulation of the Escherichia coli O157:H7 pO157 ecf operon and lipid A myristoyl transferase activity involves intrinsically curved DNA. Mol. Microbiol. 51:419-435.
  • Ely B., Ely T.W, Crymes W.B. Jr, Minnich S.A. 2000. A family of six flagellin genes contributes to the Caulobacter crescentus flagellar filament. J. Bacteriol. 182:5001-5004.
  • Rohde J.R., Luan X.S., Rohde H., Fox J.M., Minnich S.A. 1999. The Yersinia enterocolitica pYV virulence plasmid contains multiple intrinsic DNA bends which melt at 37 degrees C. J Bacteriol 181:4198-4204.

Participações em vídeos

Ligações externas

Referências

  1. 1,0 1,1 Scott Minnich, Ph.D.. Página visitada em 2016-05-16.
  2. Scott Minnich, Fellow - Center for Science and Culture. Página visitada em 2016-05-16.