Hemoglobin: Difference between revisions

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== Genetics ==
== Genetics ==
Due to problems and mutations in globin gene regulation, there are two kinds of hemoglobins produced; normal and abnormal hemoglobins.
Due to problems and mutations in globin gene regulation, there are two kinds of hemoglobins that are produce, normal and abnormal hemoglobins.
=== Normal Hemoglobin ===
=== Normal Hemoglobin ===
One can express the hemoglobin level as the amount of hemoglobin in grams (gm) per deciliter (dl) of blood. (a deciliter = 100 milliliters)
One can express the hemoglobin level as the amount of hemoglobin in grams (gm) per deciliter (dl) of blood. (1 deciliter = 100 milliliters)


Depending on the age, beginning in adolescence, and the gender of the person, the normal ranges for hemoglobin may vary.
The normal ranges for Hemoglobin is changeable because of differences in age and the gender of the person.


* Newborns: 17-22 gm/dl  
* Newborns: 17-22 gm/dl  
* One week of age: 15-20 gm/dl  
* One week old: 15-20 gm/dl  
* One month of age: 11-15gm/dl  
* One month old: 11-15gm/dl  
* Children: 11-13 gm/dl  
* Children: 11-13 gm/dl  
* Adult males: 14-18 gm/dl  
* Male Adults: 14-18 gm/dl  
* Adult women: 12-16 gm/dl  
* Female Adults: 12-16 gm/dl  
* Men after middle age: 12.4-14.9 gm/dl  
* Men after middle age: 12.4-14.9 gm/dl  
* Women after middle age: 11.7-13.8 gm/dl <ref name=medicine/>
* Women after middle age: 11.7-13.8 gm/dl <ref name=medicine/>
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==== Low Hemoglobin ====
==== Low Hemoglobin ====
Usually, a low hemoglobin is referred to as anemia. However, there are more causes of low hemoglobin besides anemia;
Usually, a low hemoglobin causes to have anemia. However, there are more causes of low hemoglobin besides anemia;
* Anemia (various types)
 
* Loss of blood (traumatic injury, surgery, bleeding colon cancer or stomach ulcer)  
* Loss of blood (because of injury, surgery, bleeding colon cancer or stomach ulcer)  
* Malnutrition (deficiency of iron, vitamin B12, folate)
* Malnutrition (deficiency of iron or vitamin B12)
* Erythropoietin deficiency (from kidney disease)  
* Erythropoietin deficiency (due to kidney disease)  
* Lead poisoning  
* Lead poisoning  
* Overhydration  
* Overhydration  
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==== High Hemoglobin ====
==== High Hemoglobin ====
People who smoke or live at high altitudes can have higher than normal hemoglobin levels. Dehydration is the main cause that produces a falsely high hemoglobin. However, When proper fluid balance is replaced, the high level of hemoglobin disappears.  
People who smoke or live at high altitudes can have higher hemoglobin levels than those who do not smoke. Dehydration is the main cause that produces a high hemoglobin. However, unlike other serious diseases, people can lower their high hemoglobin levels easily.  


There are more causes that lead high hemoglobin;
There are more causes that make high hemoglobin levels;
* Advanced lung disease (for example, emphysema),
* Advanced lung disease (emphysema)  
* Congenital heart disease
* Congenital heart disease
* Tumors
* Tumors
* Polycythemia rubra vera
* Polycythemia rubra vera
* Increased red blood cells because of too much erythropoietin  
* Increased red blood cells (due to erythropoietin)
* Low blood oxygen levels  
* Low blood oxygen levels  
* Pulmonary fibrosis <ref name=medicine/> <ref name=plus/>
* Pulmonary fibrosis <ref name=medicine/> <ref name=plus/>
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