Hemoglobin: Difference between revisions

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== Discovery ==
== Discovery ==
In 1840, at Leipzig University in Germany, the hemoglobin protein that carries oxygen was initially discovered by Hünefeld. In 1851, publishing the articles about diluting red blood cells with a solvent such as pure water (H<sub>2</sub>O) or alcohol, Otto Funke, a German physiologist, described growing hemoglobin crystals. A few years later, Felix Hoppe-Seyler, a German physiologist and chemist, investigated the binding of oxygen to erythrocytes as a function of hemoglobin, which is called the process of creating the compound oxyhemoglobin. Obtaining hemoglobin in crystalline form, Hoppe-Seyler discovered that hemoglobin contains iron. <ref> [http://www.britannica.com/EBchecked/topic/271586/Ernst-Felix-Immanuel-Hoppe-Seyler Ernst Felix Hoppe-Seyler] Encyclopædia Britannica Online </ref> In 1959, using X-ray crystallography, Max Perutz, an Austrian-British molecular biologist, established the molecular structure of hemoglobin and his work helped him win the Nobel Prize for Chemistry in 1962. <ref> [http://www.answers.com/topic/max-perutz Max Perutz] Answers.com </ref> <ref> [http://en.wikipedia.org/wiki/Hemoglobin#Research_history Hemoglobin] Wikipedia.org </ref>
In 1840, at Leipzig University in Germany, the hemoglobin protein that carries oxygen was discovered by Hünefeld first. In 1851, in his articles about diluting red blood cells with a solvent such as pure water (H<sub>2</sub>O) or alcohol, Otto Funke, a German physiologist, explained "growing hemoglobin crystals." A few years later, Felix Hoppe-Seyler, a German physiologist and chemist, discovered the binding of oxygen to erythrocytes that is one of hemoglobin's functions. This discovery is also called the process of creating the compound oxyhemoglobin. After studying hemoglobin in crystalline form, Hoppe-Seyler discovered that hemoglobin contains iron. <ref> [http://www.britannica.com/EBchecked/topic/271586/Ernst-Felix-Immanuel-Hoppe-Seyler Ernst Felix Hoppe-Seyler] Encyclopædia Britannica Online </ref> In 1959, using X-ray crystallography, Max Perutz, an Austrian-British molecular biologist, established the molecular structure of hemoglobin. His great discovery helped him win the Nobel Prize for Chemistry in 1962. <ref> [http://www.answers.com/topic/max-perutz Max Perutz] Answers.com </ref> <ref> [http://en.wikipedia.org/wiki/Hemoglobin#Research_history Hemoglobin] Wikipedia.org </ref>


== Genetics ==
== Genetics ==
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