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Mutation: Difference between revisions
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Since the base pairs of a sequence may also be part of one or more other sequences, if a mutation substitutes a nucleotide with a different one, entropy may result to any sequences that share the nucleotide. For example, it is common in eukaryotic cells that a given genetic sequence may code for multiple proteins or mRNAs, such as the human cSlo sequence which codes for 576 variants.<ref>[http://www.cell.com/neuron/abstract/S0896-6273(00)80444-4 Tune, but What Are the Instruments?] by [[Douglas L. Black]]. ''[[Neuron]]'' , Vol. 20, 165–168, February, 1998</ref>. It may also be that a sequence which expresses a protein may share nucleotide with a sequence which functions to regulate gene expression, causing entropy to both genes simultaneously, which can be understood by the statement of Dr. John Stamatoyannopoulos, a genome scientist who led a team that discovered a second code hidden in DNA, | Since the base pairs of a sequence may also be part of one or more other sequences, if a mutation substitutes a nucleotide with a different one, entropy may result to any sequences that share the nucleotide. For example, it is common in eukaryotic cells that a given genetic sequence may code for multiple proteins or mRNAs, such as the human cSlo sequence which codes for 576 variants.<ref>[http://www.cell.com/neuron/abstract/S0896-6273(00)80444-4 Tune, but What Are the Instruments?] by [[Douglas L. Black]]. ''[[Neuron]]'' , Vol. 20, 165–168, February, 1998</ref>. It may also be that a sequence which expresses a protein may share nucleotide with a sequence which functions to regulate gene expression, causing entropy to both genes simultaneously, which can be understood by the statement of Dr. John Stamatoyannopoulos, a genome scientist who led a team that discovered a second code hidden in DNA, | ||
“The fact that the genetic code can simultaneously write two kinds of information means that many DNA changes that appear to alter protein sequences may actually cause disease by disrupting gene control programs or even both mechanisms simultaneously.”<ref>[https://www.sciencedaily.com/releases/2013/12/131212142151.htm | “The fact that the genetic code can simultaneously write two kinds of information means that many DNA changes that appear to alter protein sequences may actually cause disease by disrupting gene control programs or even both mechanisms simultaneously.”<ref>[https://www.sciencedaily.com/releases/2013/12/131212142151.htm Scientists discover double meaning in genetic code] by [[John Stamatoyannopoulos]]. ''[[Science Daily]]'' December 12, 2013.</ref> | ||
This poses a great conundrum for evolution theory. Evolutionists claim that the base mechanism of evolution is mutations which increasing genetic information and ultimately define new anatomical structures and biological function. Yet many mutations cause genetic entropy which is compound because of the compressed nature of genomes. Therefore, to believe that accruing mutation designs new information, features and functions is like believing that one can walk uphill by taking one step forward and two steps backward, and any mutation which is fixed in a genome should be carefully considered before it is said to be truly neutral. | This poses a great conundrum for evolution theory. Evolutionists claim that the base mechanism of evolution is mutations which increasing genetic information and ultimately define new anatomical structures and biological function. Yet many mutations cause genetic entropy which is compound because of the compressed nature of genomes. Therefore, to believe that accruing mutation designs new information, features and functions is like believing that one can walk uphill by taking one step forward and two steps backward, and any mutation which is fixed in a genome should be carefully considered before it is said to be truly neutral. | ||
