Nitrosamine: Difference between revisions

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Some Nitrosamines are rare and are not produced commercially such as MNNG, N-Nitrosodi-n-butylamine, and many others which are solely for research purposes. N‑Nitrosodiethylamine was once widely used in  gasoline, lubricants, and much more.<ref name=pdf/> In 2001 and 2003 studies proved that many rubber products such as balloons contain a potentially dangerous amount of Nitrosamines. Upon examination in 2001, of 16 balloons 81% released dangerous amounts of nitrosamines and in 2003 93% of 14 balloons. After more tests the conclusion was that nitrosamines in rubber poses 1.5 to 3 times greater danger than food.<ref name=mig> Altkofer, Werner. [http://onlinelibrary.wiley.com/doi/10.1002/mnfr.200400050/abstract;jsessionid=F197DDA37BFEBCC2FB11BAA5A0780520.f01t01 Migration of nitrosamines from rubber products] ''Wiley Online Library'' Web. First published 25 JAN 2005.</ref>The Nitrosamines MNNG was once used for the preparation of the explosive diazomethane because it released toxic diazomethane gas. N-Nitroso-N-ethylurea has been used to help synthesize diazoethane and as a plant growth enhancer.<ref name=pdf>
Some Nitrosamines are rare and are not produced commercially such as MNNG, N-Nitrosodi-n-butylamine, and many others which are solely for research purposes. N‑Nitrosodiethylamine was once widely used in  gasoline, lubricants, and much more.<ref name=pdf/> In 2001 and 2003 studies proved that many rubber products such as balloons contain a potentially dangerous amount of Nitrosamines. Upon examination in 2001, of 16 balloons 81% released dangerous amounts of nitrosamines and in 2003 93% of 14 balloons. After more tests the conclusion was that nitrosamines in rubber poses 1.5 to 3 times greater danger than food.<ref name=mig> Altkofer, Werner. [http://onlinelibrary.wiley.com/doi/10.1002/mnfr.200400050/abstract;jsessionid=F197DDA37BFEBCC2FB11BAA5A0780520.f01t01 Migration of nitrosamines from rubber products] ''Wiley Online Library'' Web. First published 25 JAN 2005.</ref>The Nitrosamines MNNG was once used for the preparation of the explosive diazomethane because it released toxic diazomethane gas. N-Nitroso-N-ethylurea has been used to help synthesize diazoethane and as a plant growth enhancer.<ref name=pdf>


== Dangers ==
== Dangers ==  
[[File:Example.jpg|left|thumb|150px|description]]
[[File:Example.jpg|left|thumb|150px|description]]


Most Nitrosamines are considered as having the possibility of serious health problems, most notably Cancer. When nitrite is consumed it combines with amino acids in the stomach and produces Nitrosamines. Handling rubber and latex products containing Nitrosamines can cause a risk to disease as well. Studies show that with the increase of nitrite in the environment can lead to food causing diseases such as Alzheimer's, Parkinson's and diabetes Type 2. Dr. Suzanne de la Monte states that our diets have become full of nitrites and amines which combine to form Nitrosamines, causing diseases and most commonly cancer. Not only do Nitrosamines pose a danger to human life, but even a more deadly threat to animals.<ref name=health> Sahelian, Ray. [http://www.raysahelian.com/nitrosamine.html Nitrosamine health danger] ''Ray Sahelian, M.D." Web. Last updated Feb 15 2014.</ref>
Most Nitrosamines are considered as having the possibility of serious health problems, most notably Cancer. When nitrite is consumed it combines with amino acids in the stomach and produces Nitrosamines. Handling rubber and latex products containing Nitrosamines can cause a risk to disease as well. Studies show that with the increase of nitrite in the environment can lead to food causing diseases such as Alzheimer's, Parkinson's and diabetes Type 2. Dr. Suzanne de la Monte states that our diets have become full of nitrites and amines which combine to form Nitrosamines, causing diseases and most commonly cancer. Not only do Nitrosamines pose a danger to human life, but even a more deadly threat to animals.<ref name=health> Sahelian, Ray. [http://www.raysahelian.com/nitrosamine.html Nitrosamine health danger] ''Ray Sahelian, M.D." Web. Last updated Feb 15 2014.</ref>


In 1956, two British scientists were inspecting chemicals used in dry cleaning when they came upon Nitrosamines. John Barnes and Peter Magee confirmed that Nitrosamines caused tumors to grow in rats after exposure. This discovery alarmed scientists, who rapidly began testing about 300 compounds for cancer causing Nitrosamines. The result was that an astonishing 90% were potentially possible to cause cancer. Barnes and Magee’s observation that certain Nitrosamines cause certain diseases such as dimethylnitrosamine causing liver cancer, was confirmed in 1970 by an epidemic of liver cancer in Norway. The animals were discovered to have been feed fish that was exposed to large quantities of sodium nitrite for preserving.<ref name=cancer> Scanlan, Richard. [http://lpi.oregonstate.edu/f-w00/nitrosamine.html Nitrosamines and Cancer] ''Oregon State University''. Web. Last updated November, 2000.</ref> Dr. Dominique S. Michaud’s studies also show that the risk of bladder cancer was increased by 60% specifically in people who ate bacon more than 5 times a week. Nitrosamines have been suspected to also promote the growth of Glioma, a severe tumor affecting the nervous system, but no real connection has been made.<ref name=health/>
In 1956, two British scientists were inspecting chemicals used in dry cleaning when they came upon Nitrosamines. John Barnes and Peter Magee confirmed that Nitrosamines caused tumors to grow in rats after exposure. This discovery alarmed scientists, who rapidly began testing about 300 compounds for cancer causing Nitrosamines. The result was that an astonishing 90% were potentially possible to cause cancer. Barnes and Magee’s observation that certain Nitrosamines cause certain diseases such as dimethylnitrosamine causing liver cancer, was confirmed in 1970 by an epidemic of liver cancer in Norway. The animals were discovered to have been feed fish that was exposed to large quantities of sodium nitrite for preserving.<ref name=cancer> Scanlan, Richard. [http://lpi.oregonstate.edu/f-w00/nitrosamine.html Nitrosamines and Cancer] ''Oregon State University''. Web. Last updated November, 2000.</ref> Dr. Dominique S. Michaud’s studies also show that the risk of bladder cancer was increased by 60% specifically in people who ate bacon more than 5 times a week. Nitrosamines have been suspected to also promote the growth of Glioma, a severe tumor affecting the nervous system, but no real connection has been made.<ref name=health> Sahelian, Ray. [http://www.raysahelian.com/nitrosamine.html Nitrosamine health danger] ''Ray Sahelian, M.D." Web. Last updated Feb 15 2014.</ref>
 


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== Video ==
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