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Apoptosis: Difference between revisions
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'''Apoptosis''', programmed [[cell]] death, is a hot issue to biologists and scientists. It occurs in multicellular organisms with active process. Apoptosis occurs by cell shrinkage, protein fragmentation, chromatin condensation, [[DNA]] degradation and collapse of cell. [http://www.nature.com/nature/insights/6805.html] | '''Apoptosis''', programmed [[cell]] death, is a hot issue to biologists and scientists. It occurs in multicellular organisms with active process. Apoptosis occurs by cell shrinkage, protein fragmentation, chromatin condensation, [[DNA]] degradation and collapse of cell. [http://www.nature.com/nature/insights/6805.html] | ||
Cells die in three different ways: apoptosis, autophagy (autophagic type II cell death)<ref>{{cite journal|author=Gozuacik D.; Kimchi A|title=Autophagy as a cell death and tumor suppressor mechanism|journal=Oncogene|year=2004|month=Apr|Date=Apr 12, 2004|volume=23|issue=16|pages=2891-906|issn=0950-9232}}</ref> and necrosis.<ref>{{cite journal|author=Giorgi C; Romagnoli A; Pinton P; Rizzuto R.|title=Ca2+ signaling, mitochondria and cell death|journal=Curr Mol Med|year=2008|month=Mar|volume=8|issue=2|pages=119-30|pmid=18336292|issn=1566-5240|url=http://endif.unife.it/dipartimento/medicina-sperimentale-diagnostica/sezioni-centri/sezione-di-patologia-generale/signaltransductionlab/publications/55.pdf}}</ref> Apoptosis and necrosis can be similar, but they are very different. Apoptosis is controlled process for number of cells, but necrosis is dying cells by swelling and bursting. Unlikely necrosis, apoptosis is integral process. Body weight is balanced, body, body shape, separating digits, and making right neuronal connections occur by apoptosis. [http://www.scq.ubc.ca/?p=350] | Cells die in three different ways: apoptosis, autophagy (autophagic type II cell death)<ref>{{cite journal|author=Gozuacik D.; Kimchi A|title=Autophagy as a cell death and tumor suppressor mechanism|journal=Oncogene|year=2004|month=Apr|Date=Apr 12, 2004|volume=23|issue=16|pages=2891-906|issn=0950-9232|url=http://www.readcube.com/articles/10.1038/sj.onc.1207521}}</ref> and necrosis.<ref>{{cite journal|author=Giorgi C; Romagnoli A; Pinton P; Rizzuto R.|title=Ca2+ signaling, mitochondria and cell death|journal=Curr Mol Med|year=2008|month=Mar|volume=8|issue=2|pages=119-30|pmid=18336292|issn=1566-5240|url=http://endif.unife.it/dipartimento/medicina-sperimentale-diagnostica/sezioni-centri/sezione-di-patologia-generale/signaltransductionlab/publications/55.pdf}}</ref> Apoptosis and necrosis can be similar, but they are very different. Apoptosis is controlled process for number of cells, but necrosis is dying cells by swelling and bursting. Unlikely necrosis, apoptosis is integral process. Body weight is balanced, body, body shape, separating digits, and making right neuronal connections occur by apoptosis. [http://www.scq.ubc.ca/?p=350] | ||
Apoptosis has two pathways: extrinsic and intrinsic. Extrinsic pathways deliver apoptotic messages, and intrinsic pathways transmit death signals. [http://www.apoptosisworld.com/] | Apoptosis has two pathways: extrinsic and intrinsic. Extrinsic pathways deliver apoptotic messages, and intrinsic pathways transmit death signals. [http://www.apoptosisworld.com/] | ||
