110,311
edits
Hemostasis: Difference between revisions
From CreationWiki, the encyclopedia of creation science
Jump to navigationJump to search
no edit summary
No edit summary |
No edit summary |
||
| Line 19: | Line 19: | ||
== Coagulation == | == Coagulation == | ||
[[ | [[File:Coagulation Process.jpg|right|thumb|200px|The process of coagulation]] | ||
Coagulation (or blood clotting) is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin'''; another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.<ref name=wile327>Wile, Jay L., and Shannon, Marilyn M. ''The Human Body: Fearfully and Wonderfully Made!''. Cincinnati: Apologia Educational Ministries, Inc., 2001. Print.(P327-328)</ref>. | Coagulation (or blood clotting) is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin'''; another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.<ref name=wile327>Wile, Jay L., and Shannon, Marilyn M. ''The Human Body: Fearfully and Wonderfully Made!''. Cincinnati: Apologia Educational Ministries, Inc., 2001. Print.(P327-328)</ref>. | ||
| Line 28: | Line 28: | ||
Blood clotting system is controlled by antithrombin III, heparin, protein C, vitamin K, and warfarin (Coumadin). Antithrombin III is a plasma protein (a serpin) prevents the formation of thrombin by binding to prothrombin. Heparin is a mixture of polysaccharides that bind to antithrombin III. Protein C is a protein that sits at the center of the control mechanism system. It excess thrombin binds to cell-surface receptors, called thrombomodulin. Vitamin K is a cofactor needed for the synthesis of protein S. Lastly, warfarin is another name of blood thinner because it is an effective vitamin K antagonist.<ref name=Kimball/> | Blood clotting system is controlled by antithrombin III, heparin, protein C, vitamin K, and warfarin (Coumadin). Antithrombin III is a plasma protein (a serpin) prevents the formation of thrombin by binding to prothrombin. Heparin is a mixture of polysaccharides that bind to antithrombin III. Protein C is a protein that sits at the center of the control mechanism system. It excess thrombin binds to cell-surface receptors, called thrombomodulin. Vitamin K is a cofactor needed for the synthesis of protein S. Lastly, warfarin is another name of blood thinner because it is an effective vitamin K antagonist.<ref name=Kimball/> | ||
[[Image:Blood_coagulation.png|thumb|250px|Biochemical blood coagulation cascade.]] | |||
== References == | == References == | ||
{{reflist}} | {{reflist}} | ||
| Line 41: | Line 40: | ||
[[category:human biology]] | [[category:human biology]] | ||
[[category:biological process]] | [[category:biological process]] | ||
[[category:biochemistry]] | |||
