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Jaehoon Jang (talk | contribs) |
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[[File:Coagulation Process.jpg|left|thumb|200px|It shows the process of coagulation]] | [[File:Coagulation Process.jpg|left|thumb|200px|It shows the process of coagulation]] | ||
'''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin''' | '''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin'''; another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.<ref name=wile327>Wile, Jay L., and Shannon, Marilyn M. ''The Human Body: Fearfully and Wonderfully Made!''. Cincinnati: Apologia Educational Ministries, Inc., 2001. Print.(P327-328)</ref>. | ||
== Process == | == Process == |