Dopamine: Difference between revisions

The injectable form of dopamine hydrochloride, USP, is an almost transparent, aqueous, addictive solution for infusion into the bloodstream after dilution. Each mL will contain either 40mg, 80mg, or 160mg of dopamine in water for infusion including 9 mg of sodium metabisulfate as an antioxidant. With a pH level between 2.5 and 5, it may be adjusted by either citric acid or sodium citrate. The solution is disinfected and nonpyrogenic. Dopamine is a naturally occurring catecholamine and an inotropic vasopressor agent. It’s full chemical name is 3,4 dihydroxyphenethylamine hydrochloride. Dopamine is sensitive to alkali metals, iron salts and oxidizing agents. Dopamine must be appropriately diluted in a sterile parenteral solution before injection. <ref name=Rx>[http://www.rxlist.com/dopamine-drug.htm Dopamine(hydrochloride) Injection, USP] RxList, RxList, 10/4/10.</ref> Dopamine is a catecholamine, both a neurotransmitter and hormone. It also functions as a monomine, a compound that contains nitrogen formed by ammonia through the replacement of one or more of the hydrogen atoms by hydrocarbon radicals.  Dopamine is usually released prior to a release of adrenaline or noradrenaline. The decarboxylation of dopa produced dopamine. http://www.medterms.com/script/main/art.asp?articlekey=14345 <ref name=MN>[http://www.medterms.com/script/main/art.asp?articlekey=14345 Definition of Dopamine] MedicineNet.com, last edited: 3/19/04.</ref>