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Hemostasis: Difference between revisions
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[== Coagulation == | [== Coagulation == | ||
[[File:Example.jpg|left|thumb|150px|description]] | [[File:Example.jpg|left|thumb|150px|description]] | ||
'''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin''' is another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.<ref name=wile327>Wile, Jay L., and Shannon, Marilyn M. ''The Human Body: Fearfully and Wonderfully Made!''. Cincinnati: Apologia Educational Ministries, Inc., 2001. Print.(P327-328)</ref>. | '''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin''' is another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.<ref name=wile327>Wile, Jay L., and Shannon, Marilyn M. ''The Human Body: Fearfully and Wonderfully Made!''. Cincinnati: Apologia Educational Ministries, Inc., 2001. Print.(P327-328)</ref>. | ||
== Process == | |||
Hemostasis is composed of four major processes in a set order. '''Vascular constriction''' is the first step of hemostasis. It stops the blood flow to the area that is injured. When a person gets injured, Vascular contriction occurs to prevent excessive bleeding. After vascular constriction, thrombin activates platelets and they aggregate at the site of the injury, and loose platelet fibrogen. | |||
<ref name=blood coagulation>>[http://themedicalbiochemistrypage.org/blood-coagulation.html The Medical Biochemistry] Michael W. King, Ph.D, IU School of Medicine, February 24, 2011.</ref> | |||
== References == | == References == | ||
