Hemostasis: Difference between revisions

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== Coagulation ==
== Coagulation ==
[[File:Example.jpg|left|thumb|150px|description]]
[[File:Example.jpg|left|thumb|150px|description]]
'''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is produced by the liver and the liver puts prothrombinase into the bloodstream.  
'''Coagulation''' is the most complex stage of hemostasis. There are three steps in coagulation: Prothrombinase, thrombin, and fibrin. '''Prothrombinase''' is an enzyme that is produced when blood vessels or some other tissues are damaged. Prothrombinase is also called 'coagulation factor II' (F2). Prothrombinase occurs in blood plasma. Prothrombin is produced by the liver and the liver puts prothrombinase into the bloodstream. The next step is '''thrombin''' is another enzyme that prothrombinase converts prothrombin. After the second step, thrombin, the last step occurs when thrombin interacts with '''fibrinogen'''. Fibrinogen is one of the proteins in blood plasma. Fibrinogen is converted into fibrin when thrombin interacts with fibrinogen.
 
 
 
 
a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or obstructive clotting (thrombosis).


== References ==
== References ==
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