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Summary
Arbidol, ethyl-6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-indole-3-carboxylate hydrochloride monohydrate (Fig. 1), is an antiviral active chemical entity. It has been in use in Russia for several years for the treatment of influenza. The compound exerts its effect by activation upon phagocytic activity of the macrophages, and also stimulates some forms of cellular and humoral immunity. Arbidol inhibits viruses of influenza type A and type B and has the capacity to induce serum interferon. Metabolic and pharmacokinetic studies in animals have shown that orally administered arbidol is rapidly absorbed and distributed quickly into tissues and organs. (Metz, Rainer et al. "Sensitive high-performance liquid chromatographic determination of arbidol, a new antiviral compound, in human plasma", Journal of Chromatography A
Volume 810, Issues 1-2 , 12 June 1998, Pages 63-69)
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| current | 22:57, 27 April 2008 |  | 241 × 94 (7 KB) | Mcastor | Arbidol, ethyl-6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-indole-3-carboxylate hydrochloride monohydrate (Fig. 1), is an antiviral active chemical entity. It has been in use in Russia for several years for the treatment of |
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